Psoriasis is a common, chronic, relapsing/remitting, immune mediated systemic disease.. Maximum output with some simple thoughts...
Psoriasis is a non infectious, inflammatory disease of the skin. It is characterized by well defined erythematous reddish plaques with large adherent silvery scales. The main abnormality in psoriasis is an increased proliferation of the skin layers due to excessive division of the cell in the basal layers of the skin. Severe itching may associate with the plaques. Dryness of the skin and silvery scaling are characteristics of this condition.
1Percent to 3Percent of the most population has Psoriasis. It is very common among Europeans and North Americans. It is often seen between 15 to 40 yrs of age. The exact reason behind Psoriasis is unknown. There is frequently a genetic predisposition. A child with one affected parent has a 15Percent chance of developing the disease and this rises to 50Percent if both the parents are affected. Streptococcal infection of the upper respiratory tract may exacerbate the condition. Deprivation of sunlight influences this condition and mental stress plays an important role in aggravating the condition. Certain drugs like chloroquine, chlorpropamide, lithium and practaol may aggravate this condition. The peculiar lesions will be raised and red with dry, silvery white scaling. Size may vary from a few millimeters to several centimeters in diameter. Common sites are scalp elbows knees and lower back. Pitting of the nails is very common. Involvements of palm is not uncommon. Many may develop sero negative inflammatory arthritis, which is characterized by multiple involvements of joints and pitting on nails.